Two group of patients were selected. Group 1 represents 46 patients that received ovarian-biostimulation monthly for three months. Group 2 represents 32 patients that received antioxidant therapy daily for 3 months. Results are noted and analysed. Both groups represent patients with procedures already ongoing, and with diagnosed poor or depleted ovarian reserve. The analysis has been made to compare the efficacy of both procedures.
The bioestimulation group received a blood rich platelet therapy monthly for three months, with a technique developed by the laboratory. The second group of antioxidants received a combination of antioxidants monthly for three months. Both groups were compared to assess the results in terms of ovarian response (number of astral follicles, AMH levels, FSH, LH), and egg quality, embryo development, implantation rate, and successful pregnancy with healthy live birth.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
78
Injection of blood rich platelet into the ovaries.
Antioxidants: Q10, DHEA, Vitamina E, Vitamin C, Omega 3
Fertiaguerrevere Fertility
Caracas, Disfrito Federal, Venezuela
variation of hormones FSH and LH directly involved with ovarian reserve
Both groups are compared after bio-stimulation and antioxidant therapy is performed to access any possible changes with FSH-LH post-treatment.
Time frame: 18 months
variation of AMH directly involved with ovarian reserve in both groups
Both groups are compared after bio-stimulation and antioxidant therapy is performed to access any possible changes with AMH values.
Time frame: 18 months
variation in recruitment of antral follicles in both groups
Both groups are compared after bio-stimulation and antioxidant therapy is performed to access any possible changes with the number of astral follicles available.
Time frame: 18 months
Number of good quality eggs obtained in both groups after IVF
Egg quality is evaluated in both group of women undergoing IVF after bio-stimulation or antioxidant therapy are performed
Time frame: 18 months
Number and quality of fertilised eggs obtained in both groups after IVF
the number and quality of fertilised eggs is evaluated in both groups of women undergoing IVF after bio-stimulation or antioxidant therapy is performed.
Time frame: 18 months
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