Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization

Mohammed Al-Ghamdi51 enrolled

Overview

The primary purpose of this study was to investigate the effects of slider and tensioner techniques on pain, hip and knee ROM in lumbosacral radiculopathy patients with peripheral sensitization. A secondary purpose was to evaluate the correlation between these outcomes measurements.

Study design: Double-blind case-control trial. Methods: Fifty-one male lumbosacral radiculopathy patients with peripheral sensitization, were divided into one of the three groups: slider, tensioner, and control. The primary outcome measurements were visual analog scale (VAS) for pain, hip range of motion (ROM) during SLR test, and knee flexion ROM during slump test. The measurements were taken at baseline, after 1st, 3rd, and 6th session. Statistical Analysis: A two-way mixed design analysis of variance (MANOVA) with post-hoc (Bonferonni Correction) was used to calculate the differences with Time (baseline, 1st,3rd,6th sessions) as a within-group factor and Group (control, slider, and tensioner) as a between-group factor. The effect size was calculated with Cohen's d. Pearson's correlation was used for correlation analysis.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Radiculopathy

Interventions

Neural mobilization exercises -Tensioner techniqueOTHER

Exercise aiming to lengthen the neural structure using more than one joint.

Neural mobilization exercises -Slider techniqueOTHER

Exercise aiming to slide/glide the neural structure using more than one joint.

Transcutaneous Electrical Nerve Stimulation (TENS)OTHER

Electrotherapy device aiming to decrease patient's symptoms.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with lumbosacral radiculopathy with dominant peripheral sensitization * patients with unilateral leg pain. * patient S-LANSS score \> 12, * negative sensory and motor examination. * positive neural tissue provocation tests (straight leg raising test, slump test). * adult. * pain duration of more than 3 months. Exclusion Criteria: * S-LANSS score ≥ 12, * motor or sensory deficits, * history of back or lower extremity surgeries, * bilateral referred pain, * patients with pacemakers, cardiovascular problems, epilepsy, active malignancy, dermatological conditions, and diminished pain sensation.

Outcomes

Primary Outcomes

Visual Analog Scale

Visual analog scale was used to measure pain intensity. This scale is a 10 cm line where patients chose from 0 to 10 (when 0 mean no pain and 10 mean maximum pain)