Comparison of total infused dose of remifentanil between pain threshold index monitoring group and control group
Investigators plan to enroll pediatric patients aged between 3 and 12 years old undergoing surgery under general anesthesia with continuous infusion of 2% propofol and remifentanil. After dividing them into two groups, investigators monitor pain threshold index and wavelet index in test group and adjust remifentanil infusion to maintain both indices in desirable range, while monitoring only wavelet index and adjust remifentanil infusion to maintain wavelet index and conventional vital signs in desirable range in control group. Investigators compare consumption of remifentanil, time to extubation after surgery, and post-anesthesia care unit length of stay between both groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
180
In pain threshold index monitor, monitor patients' pain threshold index based on electroencephalography and adjust infusion rate of remifentanil and propofol according to pain threshold index
In wavelet index monitor, monitor patients' wavelet index based on electroencephalography as an indicator of depth of anesthesia and adjust infusion rate of propofol according to wavelet index
Seoul National University Hospital
Seoul, South Korea
RECRUITINGRemifentanil consumption
Total amount of infused remifentanil divided by patient's weight and total anesthesia time
Time frame: At the end of anesthesia, total anesthesia time less than 1 day
Extubation time
Elapsed time from end of surgery to extubation
Time frame: At the end of anesthesia, less than 1 hour
Post-anesthesia care unit length of stay
Length of stay at post-anesthesia care unit
Time frame: At discharge from post-anesthesia care unit, less than 1 day
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