Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders

Inclusion Criteria: * Patients * Men and women * Ages 18-50 years * Patients diagnosed with bipolar I disorder (BD-I), current mood state euthymic. * On a stable psychiatric medication regimen for at least a month prior to and during study participation Healthy Controls: * Men and women * Ages 18-50 years * Without major psychiatric illness Exclusion Criteria: * Patients * Any change in psychiatric medications within a month prior to and during study participation * Legal or mental incompetency * Intellectual disability * Current manic (YMRS \> 12) or severe depressive episode (HAM-D-17 \> 5) * Substance use disorder (abuse or dependence) with active use within the last 3 months * Significant medical or neurological illness * Prior neurosurgical procedure * History of seizures * History of ECT treatment or clinical TMS within the past three months * Implanted cardiac pacemakers * Patients who have conductive, ferromagnetic or other magnetic-sensitive metals implanted in their head or neck, or are non-removable and within 30 cm of the treatment coil. These include: * Aneurysm clips or coils * Carotid or cerebral stents * Metallic devices implanted in the head (e.g. Implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit, or ventriculo-peritoneal shunt) * Magnetically active dental implants * Cochlear/otologic implants * CSF shunts * Ferromagnetic ocular implants * Pellets, bullets, fragments less than 30 cm from the coil * Facial tattoos with metallic ink, permanent makeup less than 30 cm from the coil * Pregnant women Healthy Controls: * History of major psychiatric illness, including psychosis * Has a first-degree relative with psychosis * Active use of neuropsychoactive medications * Legal or mental incompetency * Intellectual disability * Substance use disorder (abuse or dependence) with active use within the last 3 months * Significant medical or neurological illness * Prior neurosurgical procedure * History of seizures * History of ECT treatment or clinical TMS within the past three months * Implanted cardiac pacemakers * Individuals who have conductive, ferromagnetic or other magnetic-sensitive metals implanted in their head or neck, or are non-removable and within 30 cm of the treatment coil. These include: * Aneurysm clips or coils * Carotid or cerebral stents * Metallic devices implanted in the head (e.g. Implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit, or ventriculo-peritoneal shunt) * Magnetically active dental implants * Cochlear/otologic implants * CSF shunts * Ferromagnetic ocular implants * Pellets, bullets, fragments less than 30 cm from the coil * Facial tattoos with metallic ink, permanent makeup less than 30 cm from the coil * Pregnant women