Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery

Ain Shams University80 enrolled

Overview

The purpose of this study is to evaluate the effect of sub anesthetic dose of ketamine on vasopressor (Ephedrine) requirement to prevent maternal hypotension after spinal anesthesia in caesarean section.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Anesthesia

Interventions

KetamineDRUG

patients will receive sub- anesthetic dose of ketamine 0.5 mg/kg in 3 ml of isotonic saline after spinal anesthesia

isotonic salineDRUG

patients will receive 3 ml of isotonic saline after spinal anesthesia

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Physical status American Society of Anesthesiologist(ASA) I or II. Full term pregnancy Exclusion Criteria: * ,Pre-eclampsia. * Chronic hypertension. * Cardiovascular troubles. * any contraindications to spinal anesthesia as back infection , coaguolopathy , patient refusal

Locations (1)

Ain Shams University hospitals

Cairo, Egypt

Outcomes

Primary Outcomes

incidence of hypotension

after spinal anesthesia sub- anesthetic dose of ketamine will be given and blood pressure will be recorded every 2 minutes till delivery , every 5 minutes till end of surgery

Time frame: 5 hours

Data from ClinicalTrials.gov

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