Transbronchial Lung Biopsy Guided by ENB

Inclusion Criteria: * 18 years and older; * Subject presents with PLL(s) detected by chest CT scan and biopsy diagnosis is needed; * Subject is willing to receive bronchoscopy voluntarily, and meets relevant requirements; * Subject or their guardian understands the purpose of this trial, and willing to participate in the trial voluntarily and sign Informed Consent Form (ICF). Exclusion Criteria: * Subject has participated in a drug or device study (drug study within 3 months or device study within 1 month); * Female subject who is pregnant or nursing; * Allergic to anesthetic; * Bronchoscopy contraindications, include: Active hemoptysis; Newly developed myocardial infarction or unstable angina attack; Severe cardiac and pulmonary dysfunction; Severe hypertension and arrhythmia; Uncorrectable bleeding tendency (Such as severe clotting dysfunction, uremia, and severe pulmonary hypertension, etc.); Severe superior vena cava obstructive syndrome; Suspected aortic aneurysm; Multiple lung bullae; Extremely exhausted systemic conditions; * Subject with serious lung disease (Such as: severe bronchiectasis, severe emphysema, etc) ,which investigator considers not appropriate for this examination; * Subject with implanted pacemaker or defibrillator; * Lack of patient cooperation for bronchoscopy, such as patient with mental disorders, dysgnosia, psychological disorder etc; * Conditions investigator considers not appropriate for this trial.