Effects of Cannabis Abstinence on Symptomology and Cognition in Bipolar Disorder

Inclusion Criteria: * All participants must be between the ages 18-60 * Meet SCID for DSM-5 diagnostic criteria for cannabis use disorder, moderate to severe * Meet SCID for DSM-5 diagnostic criteria for Bipolar Disorder (Type I or II) * Be an outpatient receiving a stable dose of mood stabilizing medication(s) for at least one month * Have a Hamilton Depression Rating Scale (HDRS-17) baseline assessment in the range of 12-25 * Have a Full-Scale IQ of at least 80 as determined by the WTAR * Be a non-treatment seeking cannabis user * Evidence of sufficient motivation and effort as measured by a Test of Memory Malingering (TOMM) score of at least 45 * Y-MRS baseline score in the range of 0-15 Exclusion Criteria: * Meets criteria for abuse or dependence of alcohol or other illicit substances within the past 6 months (with the exception of cannabis, nicotine, or caffeine) * Positive urine screen for illicit substances other than cannabis, nicotine, or caffeine * Current suicidal or homicidal ideation * Psychotic disorder diagnosis (e.g. schizoaffective disorder, major depression with psychotic features) as determined by the SCID * Treatment seeking for cannabis use * Head Injury \> 5 minutes LOC * Exceed upper and lower cut-offs on HSRD-17 and YMRS