Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in Women

Inclusion Criteria: * Women from 18 to 75 years old, * Diagnosis of primary biliary cholangitis (PBC) according to recognized criteria (EASL 2017), * Medically stable under treatment with UDCA initiated for at least 6 months, ie medically stable on the basis of liver biological parameters (no increase of more than 20% in bilirubin, ALP and transaminases) and absence of disabling pruritus (permanent and EVA\> 6/10 or scratching lesions), * Presenting a significant level of fatigue (fatigue score on PBC-40\>= 33), * Understanding the French language, * Availability and ability of the patient to access an internet network terminal to answer the online questionnaires of the study, * Signed consent form. Exclusion Criteria: * Presence of cirrhosis with a Child-Pugh B or C, * Presence of disabling pruritus (permanent, or EVA\>= 7/10 in the last 3 weeks, or objectivable scratching skin lesions), * Patient on liver transplantation waiting list or total bilirubin\> 50 μmol / L (3 mg / dL), or recent complication (\<6 months) of cirrhosis (ascites, hepatic encephalopathy, rupture bleeding) of esophageal varices), * Untreated depressive disorder, * Any comorbidity not medically controlled (i.e. all dosage changes \<3 months due to a control of the associated pathology deemed insufficient by the referring physician) or life-threatening in the medium term (within 2 years). * Psychiatric disorder modifying the relationship to the reality