Comparing Palliative Radiotherapy With or Without Carboplatin

Inclusion Criteria: * Patients with locally advanced or metastatic bronchial or head and neck cancer * Patient require palliative radiotherapy * Age ≥ 18 years * PS ≤ 2 * Obtaining the signed written consent of the patient * Patient affiliated to a social security scheme Exclusion Criteria: * Other chemotherapy or targeted therapy * Prior radiation * Patients with thrombopenia \< 100 000 * Patients with neutropenia \< 2000 * Patients with renal clearance \< 20 mL/min * Known hypersensitivity to platinum salt * Treatment with phenytoin or fosphenytoin * In previous three months, a vaccination against yellow fever, live vaccin or live attenuated vaccine * Unchecked diabetes * hemorrhagic tumor * Refusal of participation or inability to issue informed consent * Person deprived of liberty or adult under guardianship * Minor patients, pregnant or lactating women * Participation in other interventional study