Epidural vs. Wound Catheter Following Liver Resection

The Leeds Teaching Hospitals NHS Trust80 enrolled

Overview

Good postoperative pain control after any major surgery allows early mobilization, minimises postoperative complications and reduces patient distress. Multiple different methods of delivering analgesia have been described. This study aims to compare postoperative pain control between patients with epidural analgesia versus the combination of continuous infiltration of local anaesthetic with wound catheters, TAP block and IV PCA with opiate analgesia following open liver resection. The investigators expect that pain control will be similar between the two groups but that the utilization of wound catheters will confer benefit due to the lack of systemic side effects associated with epidural analgesia

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Enrollment

Conditions

Transplant Surgery

Interventions

This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All adult patients scheduled to undergo an open liver resection at this hospital will be eligible to participate. Exclusion Criteria: * Patients with a contraindication to either epidural or wound catheter * Inability to give written, informed consent * Aged less than 18 years old * Liver resection combined with a secondary surgical procedure * Body mass index of \<18 or \>40 * Pregnancy or lactation * A history of chronic pain requiring regular opioid analgesia * Prisoners

Locations (1)

Leeds Teaching Hospitals NHS Trust

Leeds, United Kingdom

Outcomes

Primary Outcomes

The length of hospital stay following open liver resection

Time frame: 6 months (or length of the study)

Data from ClinicalTrials.gov

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