Mydriatic eye drops are routinely used before phacoemulsification but they are not free of drawbacks. Several alternatives were tried to overcome their limitations.
The study will include 20 patients with bilateral cataract (40 eyes). The experimental group will include eyes for which a new injectable mydriatic combination are used to dilate the pupil. The control group will include cases where standard mydriatic eye drops are used.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
40
Experimental arm:Combined use of subconjunctival atropine sulfate 0.6 mg ( parasympathetic antagonist) and intracameral epinephrine 1:100000 ( sympathetic agonist). Control arm :topical mydriatics are used for pupil dilation.
Control arm: Preoperative cyclopentolate and phenylephrine eye drops are used.
Dar El Oyoun Hospital
Cairo, Giza Governorate, Egypt
RECRUITINGIntraoperative pupil diameter
Intraoperative pupil diameter measurements of involved eye in mm
Time frame: 1 day
Postoperative complications
Complications such as subconjunctival hemorrhage or corneal edema \[Time Frame: starting from the first postoperative day till one month\]
Time frame: Starting from first postoperative day till one month.
Postoperative corneal thickness
Measured by specular microscopy in ( mm )
Time frame: 1 month after surgery
Postoperative corneal endothelial density
Measured by specular microscopy in ( cell number/mm2)
Time frame: 1 month after surgery
Postoperative pupil diameter
Postoperative diameter of involved eye in mm
Time frame: one day, one week and one month after surgery
Postoperative visual acuity
Postoperative best corrected distance visual acuity in logmar units.
Time frame: One day, one week and one month after surgery
Postoperative intraocular pressure (IOP)
Postoperative IOP measured in mmHg
Time frame: One day, one week and one month after surgery
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