Comparing Effectiveness of Oral Misoprostal for Cervical Priming in Hysteroscopy

Department of Medical Services Ministry of Public Health of Thailand17 enrolled

Overview

Research objective To compare effectiveness of oral Misoprostal for cervical priming in premenopausal women underwent to diagnostic hysteroscopy Research hypothesis: Null hypothesis Effectiveness of oral misoprostal for cervical priming in premenopausal women underwent to diagnostic hysteroscopy is not different from placebo Alternative hypothesis: : Oral Misoprostal for cervical priming in Premenopausal women underwent to diagnostic hysteroscopy is better than placebo

Research design Randomized double-blinded placebo-controlled trial. The investigators who assess the outcomes and the participants do not know Misoprostal group or control group. The patients are given the random concealed envelop which contains Misoprostal or placebo to take before hysteroscopy. Surgeon and the investigator whom assess patients do not know group allocation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Abnormal Uterine Bleeding Chronic Pelvic Pain Infertility, Female

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Premenopausal women 2. Patients have following indication for diagnosis hysteroscopy * Abnormal uterine bleeding * Unexplained infertility * Recurrent pregnancy loss * Chronic pelvic pain * Late postpartum hemorrhage 3. Patients provided written informed consent Exclusion Criteria: 1. Postmenopausal women 2. Patients who have contraindication for Misoprostal as following * Allergic to Misoprostal * Medical illnesses such as cardiovascular diseases, Asthma, Renal disease 3. Patients who have contraindication for Hysteroscopoy as following * Pregnant women * Pelvic inflammatory disease * Infection at cervix and vagina * Cervical cancer

Comparing Effectiveness of Oral Misoprostal for Cervical Priming in Hysteroscopy

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes