The purpose of our research is to compare the effectiveness of 125mg/50ml sodium thiosulfate (STS) solution to normal saline (0.9% sodium chloride) when injected intralesionally for the treatment of calcinosis cutis. Our specific aim is to assess the response of dystrophic and idiopathic calcinosis cutis to the injections of sodium thiosulfate in our patients.
Our specific aim is to assess the response of dystrophic and idiopathic calcinosis cutis to the injections of sodium thiosulfate in our patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
5
A volume of 0.1 ml/cm2 of STS will be injected into each lesion.
A volume of 0.1 ml/cm2 of normal saline will be injected into the control lesion.
UCF Health Lake Nona Office
Orlando, Florida, United States
Lesion Size
The lesion size is measured in square centimeters.
Time frame: 3 months
Physician Global Assessment (PGA)
The PGA will be done by the physician to assess appearance and changes in the lesion. The lesion will be assigned a score from 0 (clear) to 4 (severe).
Time frame: 3 months
Visual Analog Scale (VAS) for Pain
The VAS for pain is used to assess the pain associated with the lesion. The pain will be recorded as a number from 1 (no pain) to 10 (severe pain).
Time frame: 3 months
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