Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents

Cairo University20 enrolled

Overview

To evaluate the effect of probiotics supplied in two different forms (dairy products containing probiotics as yogurt and freeze-dried synthetic probiotics sachets) on improving gingival condition and caries potentiality of dental plaque in adolescents

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Gingival Inflammation

Interventions

freeze-dried probiotic sachetsDRUG

* The participants will be instructed to consume the sachets as follow, each sachet powder is mixed with 10 ml of water in a measuring cup, then swish the mixture in the mouth for one minute before swallowing. * This procedure will be repeated once daily for the following 4 weeks. * 4 weeks supply will be given to the participants.

fermented dairy product ( yogurt)DIETARY_SUPPLEMENT

* The participants will be instructed to consume the yogurt once daily regularly for the following 4 weeks. * 4 weeks supply will be given to the participants with instruction to store the yogurt in refrigerator at home

Eligibility

Sex: ALLMin age: 12 YearsMax age: 15 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Children aged 12-15 years old 2. Children complaining from gingival problems 3. Medically free children 4. Children not registered in other clinical researches Exclusion Criteria: 1. Children with systemic diseases, mental disorders, chronic debilitating diseases. 2. Children using antibiotic treatment during the study 3. Children with orthodontic treatment 4. Children using antimicrobial mouthwash 5. Children taking any probiotic supplemental therapy

Locations (1)

Mai M Ismaiel

Cairo, Egypt

Outcomes

Primary Outcomes

Change in Gingival bleeding On Brushing

Patient questioning and answering with yes or no on a questionnaire

Time frame: base line and after 4 weeks

Secondary Outcomes

Change in Dental plaque pH

Pooled plaque sample (pH meter) on scale (1-14)

Time frame: base line and after 4 weeks

Data from ClinicalTrials.gov

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