Glaucoma is a common and potentially blinding disease. It is characterized by an optic nerve damage, a visual field defect and elevated intraocular pressure (IOP). The loss of retinal nerve fibers is accompanied by functional impairment in the territories corresponding to deficits of the visual field. However, this structure-function relationship is not always found initially. These discrepancies are mainly chronological: the structural damage preceding the functional impairment sometimes of several years
The electroretinogram pattern (ERGP) is an electrophysiological exploration technique that reflects the activity of retinal ganglion cells. It presents itself as an objective field of vision that does not require the active collaboration of the patient. It consists in recording the electrical activity of functional retinal ganglion cells following a light stimulation. Simple (30 minutes maximum), it could improve the detection of early forms of glaucoma. A significant ERGP is also thought to be correlated with peripapillary and macular CNP structural involvement of the ganglionic complex in early forms of glaucoma (MD\> -6 dB). Some results even suggest that ganglion dysfunction could be detected by the ERGP eight years on average before the occurrence of detectable alterations on the RNFL OCT. ERGP is already recognized as a routine examination for monitoring glaucomatous patients (review side in nomenclature and reimbursed by Social Security) but it could therefore be used as a diagnostic tool in very early forms of intraocular hypertonia glaucoma so to objectify signs of preperimetric functional impairment in order to establish a suitable hypotonizing treatment and to improve the prognosis of this disease.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
12
it's an additional examination that extends the duration of the ophthalmological consultation by 30 minutes
Groupe Hospitalier Paris Saint-Joseph
Paris, France
Correlations between Electroretinogram Pattern, vision field and optical coherence tomography
Electroretinogram Patterny : Magnitude, magnitude D, Magnitude D/Magnitude ratio.
Time frame: Time of inclusion
Correlations between Electroretinogram Pattern, vision field and optical coherence
Vision field: mean deviation, corrected pattern standard deviation.
Time frame: Time of inclusion
Correlations between Electroretinogram Pattern, vision field and optical coherence
Optical coherence tomography: retinal nerve fiber layer thickness and macular analysis of the ganglionic complex.
Time frame: Time of inclusion
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