Exhaled Breath Condensate Assessment in Stable Non-Cystic Fibrotic Bronchiectasis

Inclusion Criteria:Each subject must meet all of the following criteria to be included in this study: 1. Willing to join in and sign the informed consent form. 2. Age\>18 years, the diagnosis of bronchiectasis need reference to the definition of "non-cystic fibrosis bronchiectasis guideline" published by British Thoracic Society in 2010 or 2012 China bronchiectasis expert consensus, clinical symptoms of cough and expectoration, with or without intermittent hemoptysis, and chest CT showed bronchiectasis there. 3. All patients were clinically stable and had no evidence of infection or acute infective exacerbation (lower or upper respiratory tract) for at least 4 weeks before the study. 4. Patients with good compliance: the subject must be willing to follow the test plan requirements in the research center to complete all the assessment of the visit. Control Subjects: 1. All normal subjects had a negative history of allergy (negative skin prick tests to common allergens); 2. Normal lung function, and normal bronchial reactivity. 3. No history of any lung disease (except for the history of pneumonia in the past time and small pulmonary nodules). Exclusion Criteria:Subjects who meet any of the following criteria should be excluded from this study: 1. Patients with a history of other respiratory diseases (cystic fibrosis, allergic bronchopulmonary aspergillosis, asthma, 1-antitrypsin deficiency, pulmonary tuberculosis, COPD, lung cancer, interstitial lung disease)and atopic diseases were excluded； 2. Serious comorbidities (chronic renal failure, hepatic disease, etc.) ; 3. Patients were on inhaled or oral mucolytics, or were receiving oxygen therapy or long-term oral antibiotics； 4. Poor compliance or cannot cooperate judged by doctors; 5. Participated in other clinical trials for nearly three months;