Determinants of Post-Exercise Eating Patterns

Singapore Institute of Food and Biotechnology Innovation30 enrolled

Overview

This study examines potential physiological and psychological determinants of food intake in response to exercise. Specifically, beyond measuring actual food consumption and physiological markers typically assessed during exercise and appetite work (i.e. appetite hormones, blood glucose), the investigators wish to investigate the influence of individual behavioural differences (attitudes towards eating, licensing/compensatory health beliefs, self-regulation, and exercise-associated motivation) on the relationship between exercise and eating behaviour.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Obesity

Interventions

Exercise and Meal (EX)BEHAVIORAL

30 minute acute bout of high intensity intermittent exercise followed by ad-libitum meal

No-Exercise and Meal (NEX)BEHAVIORAL

30 minute non-exercise period where participants will be watching a video/movie followed by ad-libitum meal

Eligibility

Sex: MALEMin age: 21 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Male * Inactive (\< 90 min of moderate-intensity exercise a week) * BMI: 23 and above * Age between 21 to 40 years * Normal fasting blood glucose levels equal to or less than 5.9 mmol/L * Non-smoker * No know allergies or intolerance to food * Not on any prescribed medication * No physical disabilities and/or restrictions; not averse to exercising on a stationary bike or treadmill running * No aversion to blood sampling procedures (e.g. finger prick, cannulation) Exclusion Criteria: * Female, * Smoker, * Fasting blood glucose \> 5.9 mmol/L, * Resting blood pressure \> 140/90 mmHg, * Any major medical/health conditions including * Diabetes, * Metabolic disease * Hypertension, * Cardiovascular disease, * Thyroid disorders, * G6PD deficiency. * Allergic or intolerant to foods presented in the study. * Physical disabilities and/or restrictions. * Individuals that are adverse to exercising on a stationary exercise bike or treadmill. * Adverse to blood sampling procedures (i.e. cannulation, finger pricks, venepuncture).

Locations (1)

Clinical Nutrition Research Centre

Singapore, Singapore

RECRUITING

Outcomes

Primary Outcomes

Ad-libitum amount of food consumed in response to experimental condition: exercise or rest (no exercise).

Participants' eating behaviour will be assessed by measuring the total amount of the test meal consumed in each experimental condition. The test meal will be provided ad-libitum (i.e. there will be non-restricted access)

Time frame: 3 hours

Secondary Outcomes

Appetite-related blood hormone concentration in response to experimental conditions.

Venous blood will be sampled for the measurement of a range of appetite-related hormones including Active Ghrelin (pg/ml), Glucagon-like Peptide-1 (GLP-1) (pg/ml), Pancreatic YY (PYY) (pg/ml), Pancreatic Polypeptide (PP) (pg/ml), periodically through the experimental sessions.

Time frame: 3 hours

Metabolic blood variable concentration in response to experimental conditions

Venous blood will be sampled for the measurement of metabolic blood variables blood insulin (mmol/L) and blood glucose (mmol/L) periodically through the experimental sessions.

Time frame: 3 hours

Subjective ratings of hunger in response to experimental conditions

Self-reported subjective ratings of hunger will be assessed periodically through the experimental session. Assessed via 100-point visual analogue scales.

Time frame: 3 hours

Subjective ratings of satiation (fullness) in response to experimental conditions

Self-reported subjective ratings of satiation (fullness) will be assessed periodically through the experimental session. Assessed via 100-point visual analogue scales

Time frame: 3 hours

Subjective ratings of desire to eat in response to experimental conditions

Central Contacts

Aaron Y Sim, PhD

CONTACT

+6564074046 aaron_sim@sics.a-star.edu.sg

Elizabeth X Lim, BSc

CONTACT

+6564070093 elizabeth_lim@sics.a-star.edu.sg

Data from ClinicalTrials.gov

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