We aim to o evaluate the role of conventional and advanced MRI sequences in diagnosis of idiopathic temporal lobe epilepsy including identification and lateralization of epileptogenic focus.
Patients with history of partial seizures with or without secondary generalization attending at outpatient clinic or admitted at Neurology department of Assuit University Hospital will be included in the study MRI study will be done for each patient. MR imaging will be performed on a 1.5-T MR imaging unit (Siemens, Sembra medical system,German). Prospectively completed data forms will be analyzed and compared. Statistical tests appropriate to the nature of the data will be used. All patients will not be subjected to risk of any kind during this study. All patients' data will be confidentially kept. Approval of the ethical committee of Faculty of Medicine, Assiut University. An informed consent will be taken from all patients included in this study. The research will be conducted only by scientifically qualified and trained personnel. The procedures included in this study have been already used in hospital and centers in and outside Egypt
Study Type
OBSERVATIONAL
Enrollment
50
Magnetic resonance imaging with advanced sequences including volumetry, spectroscopy and tractograpghy.
Assiut university hospital
Asyut, Egypt
RECRUITINGCalculating the sensitivity,specificity and accuracy of hippocampal volumetry , T2 relaxometry , MR spectroscopy and diffusion tensor imaging in identification and lataeralization of epileptogenic focus
* Quantification of hippocampal volumes bilaterally by mean of hippocampal volumetry * Change in metabolites ratio at the affected hippocampus by mean of MR spectroscopy
Time frame: baseline
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