The investigators meant to establish a multi-centered bronchiectasis patient registry for Chinese bronchiectasis patients. This would be the first bronchiectasis registry in China. Patients with all kinds of bronchiectasis would be enrolled.
A multi-centered bronchiectasis patient registry would be founded, which will include patients from three teaching hospital (Ruijin Hospital, Zhongshan Hospital and Shanghai Pulmonary Hospital) in Shanghai at the beginning. The network will be promoted to other cities and different places in China. Patients with bronchiectasis would be enrolled and detailed information would be recorded. Follow-up of patients would provide more information on the prognosis of disease. Optimal treatment studies for the patients will be initiated one by one based on the network. The investigators are committed to promoting clinical research and education in bronchiectasis, through sharing of protocols, research idea and expertise.
Study Type
OBSERVATIONAL
Enrollment
10,000
Shanghai Pulmonary Hospital , Tongji University
Shanghai, Shanghai Municipality, China
RECRUITINGRuijin Hospital
Shanghai, China
RECRUITINGNumber of patients enrolled in the registry
To establish a multi-centered bronchiectasis registry in Shanghai
Time frame: 3 years
Lung Function (FEV1, FVC, FEV1% pred, FVC% pred etc.)
Lung function would be tested by spirometry when patients visit the clinic.
Time frame: recorded at baseline and re-tested every year, up to 3 years.
Exacerbation
Exacerbation was defined as the use of antibiotics or even hospitalization due to the worsening of symptoms or emergence of new symptoms.
Time frame: up to 3 years
Aetiology
To analysis the possible cause of bronchiectasis in Shanghai, China.
Time frame: at baseline
Microbiology
Sputum or bronchoalveolar lavage fluid culture
Time frame: At least 1 year before enrollment and 3 years during the follow-up
Comorbidity
Comorbidity would be recorded.
Time frame: At baseline and updated every year for up to 3 years
Quality of Life Questionnaire-Bronchiectasis
The questionnaire asks patients questions about their current state of health. It could be downloaded from the website online.
Time frame: At baseline and updated once a year for 3 years
Bronchiectasis severity Score (BSI)
The scale is presented online. It consists of 9 items including Age, BMI(Body Mass Index), % FEV1 Predicted, Previous Hospital Admission in the past 2 years, number of exacerbations in previous year, MRC Breathlessness Score, Pseudomonas Colonisation, Colonisation with other organisms,affected lobes. 0-4 Mild Bronchiectasis. 5 - 8 Moderate Bronchiectasis. 9 + Severe Bronchiectasis.
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Time frame: At baseline and updated once a year for 3 years
E-FACED score
It consists of 6 items including exacerbation history in the past year, % FEV1 predicted, Age, Chronic colonization by Pseudomonas aeruginosa, n° of pulmonary lobes affected,and Dyspnea (measured by mMRC score) mild: 0-3 points, moderate: 4-6 points; and severe: 7-9 points
Time frame: At baseline and updated once a year for 3 years
Mortality
Time frame: 3 years
modified Medical Research Council (mMRC) dyspnea score
1. \- Not troubled by breathlessness except on strenuous exercise 2. \- Short of breath when hurrying or walking up a slight hill 3. \- Walks slower than contemporaries on level ground because of breathlessness, or has to stop for breath when walking at own pace 4. \- Stops due to breathlessness after walking 100m 5. \- House bound due to breathlessness, or breathless on dressing or undressing.
Time frame: At baseline and updated once a year for 3 years