This study intends to evaluate the impact of resistance training variable manipulation (intensity and volume) on body composition, fatigability and functional capacity in postmenopausal breast cancer survivors.
The treatment for breast cancer (chemotherapy, radiotherapy and hormone therapy) provokes collateral effects,such as muscle mass and strength losses, increase of fat mass, fatigue and disability and reduced quality of life in postmenopausal breast cancer survivors. The resistance training is assumed as a non-pharmacologic interventions in postmenopausal breast cancer survivors. However, it is unclear whether the manipulation of training variables (intensity and volume) maximize the effects of resistance training on body composition, fatigability and functional capacity in postmenopausal breast cancer survivors.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
80
The volunteers will not performed the interventions.
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, three sets with 30% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, three sets with 80% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Post-degree program in physical education
Uberaba, MG - Minas Gerais, Brazil
RECRUITINGEvaluation the Fatigability
The fatigability will be evaluate by 60 maximum voluntary isometric contractions (3 s contraction, 2 s rest) in knee extensors at 70 degree
Time frame: pre and post intervention (i.e. 12 weeks)
Four- meter walk test
The volunteers will walk 4 meter. The time will be computed to determine the gait velocity (m/s).
Time frame: pre and post intervention (i.e. 12 weeks)
Fat mass
The fat mass (kg) will be assessed via dual-energy x-ray absorptiometry scanning (iDXA; GE Healthcare-Luna, Madison, WI; software Encore version 14.10).
Time frame: pre intervention and post intervention (i.e. 12 weeks)
Muscle strength
Muscle strength will be evaluated by one repetition maximum (1RM) test.
Time frame: pre and post intervention (i.e. 12 weeks)
Six Minutes-walk test (6MWT)
The volunteers will walk 6 minutes. The distance (meters) will be recorded after completes the test. The 6MWT will be performed indoor, on a flat floor in a sports court.
Time frame: pre and post intervention (i.e. 12 weeks)
Timed Up and Go test
The volunteers will be advised to get up from a chair, walk three meters, turn around, go back to the chair, and sit down. The time (seconds) will be recorded. The test will be performed indoor, on a flat floor in a sports court.
Time frame: pre and post intervention (i.e. 12 weeks)
Five-times-sit-to-stand test
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The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, six sets with 80% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
The volunteers will rise from a chair and returned to the seated position as quickly as possible for five repetitions. The time will be recorded (seconds).
Time frame: pre and post intervention (i.e. 12 weeks)
Muscle mass
The muscle mass (kg) will be assessed via dual-energy x-ray absorptiometry scanning (iDXA; GE Healthcare-Luna, Madison, WI; software Encore version 14.10).
Time frame: pre and post intervention (i.e. 12 weeks)
10-meter walk test
The volunteers will walk 10 meters. The gait speed will be evaluated (m/s). The test will be performed indoor, on a flat floor in a sports court.
Time frame: pre and post intervention (i.e. 12 weeks)
400-meter walk test
The volunteers will walk 400 meters. The gait speed will be evaluated (m/s). The test will be performed indoor, on a flat floor in a sports court.
Time frame: pre and post intervention (i.e. 12 weeks)
900-meter walk test
The volunteers will walk 900 meters. The gait speed will be evaluate (m/s). The test will be performed indoor, on a flat floor in a sports court.
Time frame: pre and post intervention (i.e. 12 weeks)