Assessment of Response to the Conventional Periodontal Treatment Based on the Blood Group Phenotypes.

Damascus University60 enrolled

Overview

The aim of this study is to find out if one blood group phenotype is more responsive than the others to the nonsurgical periodontal treatment.

To the best of our knowledge, this is the first (research) randomized clinical trial that assesses how patient respond to the nonsurgical periodontal treatment based on their blood group phenotype.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Periodontitis

Interventions

nonsurgical periodontal treatmentPROCEDURE

patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * systematically healthy. * have at least 20 teeth excluding the third molars. * had not received any periodontal treatment or antibiotic therapy for dental or medical reason 6 month prior to the study. * diagnosed with generalized chronic periodontitis (\>30% of the sites have probing depth ≥4), and a minimum of six teeth with probing depth of 5-6 mm. Exclusion Criteria: * smokers and alcoholics. * pregnancy. * history of a systematic disease such as diabetes, leukemia, epilepsy. * participants who are unable to perform routine oral hygiene. * use of orthodontic appliances. * participants who are unable to perform routine oral hygiene.

Locations (1)

Department of Periodontics

Damascus, Syria

Outcomes

Primary Outcomes

Change in relative attachment level.

the relative attachment level measures the length form the base of the periodontal pocket to a stent

Time frame: measures will be taken at baseline and after two months from treatment.

Secondary Outcomes

Change in periodontal probing depth.

the distance between the gingival margin to the base of the periodontal pocket.

Time frame: measures will be taken at baseline and after two months from treatment.

Change in gingival index

it is used to designate the level of the gingival inflammation.

Time frame: index will be taken at baseline and after two months from treatment.

Change in plaque Index

it is used to designate the level of plaque accumulation.

Time frame: index will be taken at baseline and after two months from treatment.

Data from ClinicalTrials.gov

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