Pharmakokinetik of Caffeine in Epiretinal Membranes After Oral Intake: a Pilot Study

Vienna Institute for Research in Ocular Surgery40 enrolled

Overview

Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry.

Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry. One hour before surgery patients in the caffeine Group will receive 180mg of caffeine. in all patients vitrectomy with Membrane Peeling will be performed, due to epiretinal membranes

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Epiretinal Membrane

Interventions

vitrectomy with membrane peelingPROCEDURE

during vitrectomy with membrane peeling a prob of the vitreous body and the excised epiretinal membrane will be harvested for gas-chromatography/mass spectrometry

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * epiretinale membrane Exclusion Criteria: * none

Locations (1)

Vienna Institute for Research in Ocular Surgery (VIROS), Hanusch Hospital Vienna

Vienna, Austria

Outcomes

Primary Outcomes

concentration of caffeine in vitreous probes and epiretinal membranes

concentration of caffeine in the probes will be measuread by gas-chromatography/mass spectrometry

Time frame: one hour

Data from ClinicalTrials.gov

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