A Pilot Study on the Use of Platelet Rich Plasma (PRP) for Facial and Hand Skin Rejuvenation

Inclusion Criteria 1. Only female patients are eligible 2. Patients must be 45 years of age or older 3. Patients must have signs of skin aging on face (wrinkles, rough texture, skin atrophy and skin laxity) and hands (loss of fat tissue and visibility of veins and tendons). 4. Patients must have been on stable birth control for the past 6 months if able to conceive 5. Patients are able and willing to provide written informed consent after the study is fully explained Exclusion Criteria 1. Patients with clinically abnormal platelet count, serum chemistry, or screening laboratory results as reviewed by the Principal Investigator 2. Patients who have had any cosmetic procedures meant to address skin aging of face and hands 3 months prior to enrollment 3. Patients who have had resurfacing laser on face or hands within one year prior to enrollment 4. Patients taking anti-rheumatic disease medication (including methotrexate or other anti-metabolites) within the 3 months prior to study entry 5. Patients who are pregnant or currently breast-feeding 6. Patients with systemic, rheumatic, or inflammatory disease or who are immunosuppressed 7. Patients with ongoing infectious disease, including HIV and hepatitis 8. Patients with history of significant cardiovascular, renal, hepatic, endocrine disease, cancer, or diabetes 9. Patients participating in a study of an experimental drug or medical device within 30 days of study entry 10. Patients with history of platelet disorders, bone marrow aplasia, sepsis, or cancer 11. Patients taking anti-aggregating therapy 12. Patients on anticoagulant therapy 13. Patients with history of keloid formation 14. Patients with uncontrolled diabetes 15. Patients with active skin disease or skin infection on the intended treatment areas, at baseline