Hepatitis C Virus (HCV) Positive Liver Grafts in HCV Negative Recipients

Inclusion Criteria: * Male or female * Age 18 and older * Active on the transplant list * Donor organ with Antibody and nucleic acid test (NAT) positive for HCV * Graft with F2 fibrosis or less at time of explant * HCV negative recipient; this includes patients who never had HCV and those with HCV previously eradicated with antiviral therapy. The latter is defined as those with undetectable HCV viral load at least 3 months since stopping therapy. * Willing and able to provide written informed consent or for those subjects where hepatic encephalopathy affects their ability to provide initial or ongoing consent, has an appropriate and legally-authorized representative willing and able to provide consent on behalf of the subject Exclusion Criteria: * Participants co-infected with HIV * Donor previously treated with a non-structural protein 5A (NS5a) containing regimen (if treatment history of donor known) * Known allergies or hypersensitivity to direct acting antiviral drug (DAA) or ribavirin (RBV) * Pregnancy and/or actively breastfeeding