Despite the importance of preventing muscle mass loss during senescence, only a few studies have investigated the relationship between diet and muscle mass in postmenopausal women. Therefore, the aim of this study is to investigate whether controlled protein consumption at the current Recommended Daily Allowance (RDA = 0.8 g/kg body weight) or twice the RDA (1.6 g/kg body weight) affects skeletal muscle mass, strength, and physical performance in postmenopausal women. In this parallel-group trial, participants were randomized for 6 months to low glycemic index diets with controlled protein consumption at the current RDA or twice the RDA, aimed to balance energy needs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
28
Change in whole-body and appendicular lean mass
measured by dual-energy X-ray absorptiometry
Time frame: 6 months
Change in isometric hand grip strength
measured by dynamometry
Time frame: 6 months
Change in usual gait speed
in a 4-m course
Time frame: 6 months
Change in systolic blood pressure
in mmHg
Time frame: 6 months
Change in diastolic blood pressure
in mmHg
Time frame: 6 months
Change in fat mass
measured by dual-energy X-ray absorptiometry
Time frame: 6 months
Change in resting metabolic rate
measured by indirect calorimetry
Time frame: 6 months
Change in total cholesterol, high-density lipoprotein cholesterol, and triglycerides
determined by colorimetric-enzymatic methods
Time frame: 6 months
Change in glucose
determined by the hexokinase method
Time frame: 6 months
Change in insulin
measured by chemiluminescence immunoassays
Time frame: 6 months
Change in high-sensitivity C-reactive protein
measured by nephelometric method
Time frame: 6 months
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