Although β-alanine (BA) has been shown to be an effective ergogenic aid, little information exists on the safety of chronic supplementation despite potential concerns. The aim of this study was to investigate the effects of chronic BA supplementation on muscle taurine content, blood clinical markers and sensory side-effects during 24 weeks of BA supplementation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Enrollment
25
Beta-alanine in sustained-release tablets to increase muscle carnosine content
Maltodextrin is used as a placebo as it does not lead to any increases in muscle carnosine
Muscle taurine content in mmol/kg
Change in the content of taurine in muscle will be determined using High-Pressure Liquid Chromatography of muscle biopsies
Time frame: Up to 24 weeks
Aspartate transaminase; alanine aminotransferase; alkaline phosphatase; lactate dehydrogenase and creatine kinase in U/L
Aspartate transaminase; alanine aminotransferase; alkaline phosphatase; lactate dehydrogenase and creatine kinase will be analysed from venous blood samples
Time frame: Up to 24 weeks
Albumin; globulin; creatinine in mg/dL
Albumin; globulin; creatinine will be analysed from venous blood samples
Time frame: Up to 24 weeks
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