This study will evaluate the effects of a pharmacist-led, deprescribing-focused medication review on the use of inappropriate medications by nursing home residents
Nursing home residents are often prescribed inappropriate medication, drugs whose negative effects outweigh potential benefits or which are not useful anymore. Inappropriate medication have been linked with worse health outcomes, hospitalisations and death. Deprescribing, the structured process of withdrawing or tapering inappropriate medications, has been studied as a potential solution to this problem. In this study, nursing home residents living in institution which are already engaged in a deprescribing process will be randomly allocated to receive a medication review or usual care. The medication review will be performed by the nursing home pharmacist an its results will be discussed with the responsible physicians and nurses to create a deprescribing plan specifically tailored to the needs of the resident.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
62
The pharmacist responsible for the nursing home will perform a medication review (type 3). The results of this review will be discussed with the physician and nurse responsible for this participant, with the goal of creating a personalised deprescribing plan. Once validated by the physician, this plan will be submitted to the participant for approval.
Centre de Pharmacie Communautaire
Lausanne, Canton of Vaud, Switzerland
Number of Inappropriate Medication at Follow-up
Number of inappropriate medications prescribed at follow-up, assessed using the French translation of STOPP v2.
Time frame: 4 months
Number of Potentially Inappropriate DDDs Prescribed to Participants at Follow-up
Appropriateness assessed using the French translation of STOPP v2; DDD defined by WHO.
Time frame: 4 months
Number of Chronic Drugs Prescribed to Participants
Number of Chronic Drugs Prescribed to Participants
Time frame: 4 months
Number of Chronic DDDs Prescribed to Participants
Number of chronic DDDs prescribed to participants
Time frame: 4 months
Number of New Drugs Prescribed as a Result of the Intervention
This outcome was not analysed
Time frame: 4 months
Health-related Quality of Life
The EuroQol 5-Dimensions 5-Levels (EQ-5D-5L) tool was used to assess quality of life; this tool includes * a visual analog scale, ranging from 0 to 100, 100 indicating "the best health you can imagine" and 0 "the worst health you can imagine". Higher results indicate an higher quality of life. * 5 questions, each with 5 possible answers. Using a valuation set, the answers to individual questions were transformed in a numeric index value for each participants, with a maximum of 1 and an infinitely low minimum. Higher values indicates higher perceived health-related quality of life.
Time frame: 4 months
Number of Common Drug-related Complaints at Follow-up
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Number of common drug-related complaints at follow-up
Time frame: 4 months