Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder

Rothman Institute Orthopaedics100 enrolled

Overview

This is a prospective, randomized controlled trial to evaluate the ability of hydrogen peroxide preparation in addition to chlorhexidine to decrease the colonization of Propionibacterium acnes(a bacteria commonly found in the dermis of the skin surrounding the shoulder in order to decrease postoperative joint infection.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

100

Conditions

Propionibacterium Infection

Interventions

a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcoholDRUG

a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol

Iodine scrub and ChloraPrep aloneDRUG

Iodine scrub and ChloraPrep alone

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1\. All male patients (\>18) undergoing shoulder arthroscopy Exclusion Criteria: 1. Female patients 2. Patients with active acne 3. Patients who have taken antibiotics within a month of their surgery 4. Subjects allergic to any of the following agents: o Benzoyl peroxide 5. Subjects with psoriatic/eczematous lesions on the shoulder girdle.

Locations (1)

Rothman Institute

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

colonization of p.acnes in the dermis of the shoulder

number of colony forming units grown in bacterial culture

Time frame: 14 days in culture

Data from ClinicalTrials.gov

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