The purpose of this clinical investigation is to evaluate the safety and effects of CCCR-modified NK92(CCCR-NK92)infusions in previously treated advanced non-small cell lung carcinoma(NSCLC).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
2
CCCR-NK92 cells will be administered intravenously over 1h. The starting dose of CCCR-NK92 cells will be 1×10e7-1×10e8,twice a week. The first evaluation of the efficacy after 3 weeks of treatment.
The first Affiliated Hospital of Xinxiang Medical University
Xinxiang, Henan, China
Number of participants with adverse events evaluated with CTCAE,version 4.0
Safety evaluation
Time frame: 3 months
Objective Response Rate
Non-small cell lung carcinoma to CCCR-NK92 cell infusions
Time frame: up to one year
Disease Control Rate
Time frame: up to one year
Progression-free Survival
Time frame: up to one year
Overall Survival
Time frame: up to one year
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