Effects of PEP on IC During IT in Patients With COPD

Cliniques universitaires Saint-Luc- Université Catholique de Louvain1 enrolled

Overview

This study will investigate the effects of positive expiratory pressure (PEP) on hyperinflation in patients with chronic obstructive pulmonary disease (COPD). Inspiratory capacity (IC) is the primary outcome

This is a cross-over intervention assessing the effect of PEP on IC and dyspnea in patients with COPD performing an interval training (IT) session. IC will be measured before, during and immediately after the IT session. Each participant will receive perform IT sessions including either the use of a PEP of 10 cmH2O or a PEP of 1 cmH2O. The effects on IC and dyspnea on both PEP levels will be assessed.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

PEP-10DEVICE

Bottle PEP with a water level of 10 cmH2O

PEP-1DEVICE

Bottle PEP with a water level of 1 cmH2O

Eligibility

Sex: ALLMin age: 45 YearsMax age: 95 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Stable COPD since 1 month at least * Able to understand the instructions Exclusion Criteria: * COPD with a forced expiratory volume at one second \> 80% of predicted values * In exacerbation * Orthopedic of neurological condition likely to interfere with the experimentation * Contraindication to perform exercise

Locations (1)

Cliniques universitaires Saint-Luc

Brussels, Belgium

Outcomes

Primary Outcomes

Change in inspiratory capacity

Evolution of inspiratory capacity while performing the interval training session

Time frame: 20 minutes

Secondary Outcomes

Change in Borg scale

Evolution of dyspnea while performing the interval training session

Time frame: 20 minutes

Data from ClinicalTrials.gov

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