A Study to Investigate the Safety, Tolerability and Pharmacokinetics of RD01 (Pegerythropoietin) in Healthy Chinese Volunteers

Inclusion Criteria: * Age 18\~60, both male and female * Healthy adults without obvious organic diseases and nervous/mental diseases * BMI 19\~26 kg/m2, inclusive * Subject is willing and able to provide written informed consent, and would complete the whole study procedures * Serum ferritin level is within the reference range at screening within 4 weeks before enrollment * Should be fully recovered, when has received surgical treatment Exclusion Criteria: * Has allergy history or past drug allergy history, or allergy history to polyethylene glycol * Has taken any drug within 5 half-time or 4 weeks before enrollment * Has taken any drug known to harm organ within 12 weeks before enrollment * Participated in other clinical trials within 12 weeks before enrollment * Donated blood or received blood transfusion, or received therapy of recombinant erythrocytogenetic stimulating protein or rHuEPO within 12 weeks before enrollment * Female subject receives therapy of hormone after menopause * Subject with clinically significant abnormal of lab tests determined by the investigator (subjects with Hb or Rtc level outrange the up-limit of reference were suggested to be excluded) * Subject with HBsAg, HBeAg, HCV-Ab, HIV-Ab or Treponema pallidum antibody positive * Clinically diagnosed as vitamin B12 or folic acid deficiency * Previous history of coronary heart disease or congestive heart failure, or ECG shows clinical significance of abnormalities * With history of malignant tumors or suspicious * Subject with active infection * History of autoimmune disease, or being treated with immunosuppressive agents * With severe, progressive or uncontrolled diseases of liver, kidney, blood, gastrointestinal tract, endocrine, heart, lung, nerves or brain * Pregnant or lactating women, or subject planning to has descendants during trial or within 12 weeks after dosing * Drug abusers, drug addicts, or smokers (5 or more cigarettes per day), alcoholics (14 or more units per week, 1 unit = 360 mL of beer or 150 mL of wine or 45 mL of alcohol 40% or more) * Other factors that might influence the attendance determined by investigators, including poor compliance (long-term travel, planned relocation, mental illness, lack of motivation, etc.)