Effect of LANCONONE in Weight-bearing Joint Pain

Inclusion Criteria: 1. BMI ≥ 25 and ≤ 29.9 kg/m2. 2. With unilateral or bilateral OA of the knee for at least greater than 3 months, as presented by pain in the knee at least for last 3 months. 3. Post-menopausal females (LMP at least 12 months prior to the screening). Exclusion Criteria: 1. History of osteoarthritis for more than 3 years. 2. Systolic Blood Pressure ≥140 mm Hg and Diastolic Blood Pressure ≥ 90 mm Hg 3. FBS\>140 mg/dl. 4. Smokers or chronic alcoholics. 5. Participants planning to travel in the next 56 days or engage in any non-routine activity that is likely to strain the knees.