Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus

Inclusion Criteria: * Subjects are newly diagnosed of T2DM according to World Health Organisation criteria) and do not receive any glucose-lowering drugs * Subjects with normal glucose tolerance test according to World Health Organisation criteria which is carried out immediately before inclusion in the study * Subjects who are willing to participate and sign the informed consent form Exclusion Criteria: * Patients with pre-existing T2DM * Patients with family history of diabetes * Patients receiving glucose-lowering medications * Patients with anemia, abnormal serum creatinine level, macroalbuminuria, proliferative retinopathy, impaired liver function