Basal-bolus insulin therapy, which includes one injection of long acting insulin and three injections of short acting insulin is the most commonly used insulin treatment. However, many older patients find the basal-bolus insulin regimen hard to manage because it involves 4 injections and 4 blood glucose tests each day. It is possible that a simplified treatment that involves one injection of long acting insulin daily and two blood glucose tests daily might be equally effective. This simplified regimen, if effective, would be easier to use and might result in less errors. Therefore, the investigators want to conduct this study to compare using a single daily injection of basal insulin with the usual basal-bolus insulin regimen in elderly patients (age \>65 years) with type 2 diabetes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
7
0.40 units/kg body weight
0.20 units/kg body weight
0.20 units/kg body weight
0.20 units/kg body weight
University of Miami
South Miami, Florida, United States
Hemoglobin A1c (HbA1c)
The mean HbA1c in the BI group will be compared to the mean HbA1c in the MSI group
Time frame: 6 months
Incidence of Any Hypoglycemia
Defined as any reported blood glucose (BG) \<70 mg/dl will be compared between the two groups
Time frame: 6 months
Incidence of Severe Hypoglycemia
Any BG \<54 mg/dl or patient requiring assistance to recover from hypoglycemia will be compared between 2 groups.
Time frame: 6 months
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