LSFG-SKIN, Laser Speckle Flowgraphy

Randy Kardon1 enrolled

Overview

The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.

Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hypertension Heart Failure Vascular Ischemia Burns Chemotherapy Effect

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Controls ●Healthy normal control subjects ages 18-90 Cardiology Subjects * Ages 18-90 * History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease Dermatology Subjects * Ages 18-90 * History of inflammatory and cancerous lesions Endocrine Subjects * Ages 18-90 * History of diabetes, thyroid disease Neurology Subjects * Ages 18-90 * History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis Psychiatry Subjects * Ages 18-90 * History of bipolar, schizophrenia, anxiety, depression Surgery Subjects * Ages 18-90 * History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures. Ophthalmology Subjects * Ages 18-90 * History of ocular disorders caused by hypo perfusion or inflammatory disorders Exclusion Criteria: Controls * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma Cardiology Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma 3\. Dermatology Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma Endocrine Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma Neurology Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma Psychiatry Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma Surgery Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma Ophthalmology Subjects * Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. * Angle closure glaucoma

LSFG-SKIN, Laser Speckle Flowgraphy

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes