Immunogenetic Profiling of Goeckerman Therapy in the Treatment of Psoriasis Vulgaris

Inclusion criteria 1. Male or female ≥ 18 years of age at enrollment. 2. Documentation of predominately moderate to severe plaque psoriasis for at least 6 months prior to enrollment. 3. Written informed consent obtained from subject and ability for subject to comply with the requirements of the study. 4. Subject is considered a candidate for phototherapy or systemic therapy 5. Body Surface Area (BSA) ≥ 5%. 6. Physical exam within clinically acceptable limits. Exclusion criteria 1. Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data. 2. Subject has predominantly non-plaque form of psoriasis. 3. Subject has drug-induced psoriasis. 4. Subject with current, or a history of, severe psoriatic arthritis well controlled on current therapy. 5. Patient has absolute or relative contraindication to phototherapy, including photosensitizing disorders. 6. Evidence of abnormality of any immune cell population from a drug-induced or genetic cause. 7. Known HIV positive status. 8. Known allergy to lidocaine, other local anesthetics, or any component of local anesthetic agents.