Performing an additional non-invasive oocyte diagnostic test based on cumulus cell gene expression could improve the outcome of the ART cycle for rFSH stimulated patients
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
100
Classification of the oocyte/embryo based on the gene expression pattern observed in the cumulus cells
Universitair Ziekenhuis Brussel
Jette, Brussels Capital, Belgium
RECRUITINGClinical pregnancy as observed by ultrasound
This observation is routinely performed by the treating physician for every patient undergoing standard ART treatment and is thus available from the fertility center database
Time frame: 2 months after embryo transfer
Positive beta-hCG pregnancy as observed by serum analysis
This observation is routinely performed by the treating physician for every patient undergoing standard ART treatment and is thus available from the fertility center database
Time frame: 12-17 days after embryo transfer
Live birth by questionnaire
This observation is routinely performed by the study nurses of the fertility center for every patient undergoing standard ART treatment and is thus available from the fertility center database. This measurement does not include a scale, there is either a child born or not. The date of delivery and the gender of the child are asked together with eventual complications.
Time frame: at least 9 months after embryo transfer
Cumulative pregnancy by ultrasound (for pregnancy follow-up) and questionnaire (for live birth follow-up) (see outcome 1 and 3)
This is the compilation of the data gathered in outcome 1 and 3 for eventual consecutive cycles. This observation is routinely performed by the study nurses of the fertility center for every patient undergoing standard ART treatment and is thus available from the fertility center database
Time frame: 2 years after embryo transfer
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