An observational cohort study of the frailty of vascular surgery patients undergoing intervention and their outcomes.
Vascular surgical operations are major procedures with significant associated morbidity and mortality. Frailty is a major factor influencing surgical outcome, but the effect on morbidity/mortality and quality of life is poorly understood in vascular surgery. Activity levels play a significant role in frailty and in pre-intervention preparation. It is anticipated that as frailty levels increase, activity levels decrease. It is hypothesised that vascular surgery patients suffer from a high prevalence of frailty and that increasing frailty will lead to increased morbidity and mortality and decreased quality of life. This initial study will provide the foundations to identify targets for improvement in degree of frailty, appropriateness for surgery and outcome. This project aims to: Assess and quantify the prevalence of frailty as well as recording activity levels in the vascular surgery patient cohort Explore the impact of frailty and pre-op activity on surgical outcomes in the vascular surgical patient cohort to guide surgical treatments as well as future studies aimed at improving frailty and activity and thereby quality of life. Identification of an appropriate metric of frailty for this population group to include activity, is a secondary aim of this proposal.
Study Type
OBSERVATIONAL
Enrollment
300
Quality of life and frailty questionnaires
Imperial College London
London, United Kingdom
NOT_YET_RECRUITINGImperial College Healthcare NHS Trust
London, United Kingdom
RECRUITINGCorrelation between electronic Frailty Index and survival and complication rate.
Survival and rate of complication correlated with the pre-operative frailty score (electronic Frailty Index).
Time frame: 6 months
Correlation between Q Mortality Index and survival and complication rate.
Survival and rate of complication correlated with the pre-operative frailty score (Q Mortality Index).
Time frame: 6 months
Correlation between ACS Risk Calculator Score and survival and complication rate.
Survival and rate of complication correlated with the pre-operative frailty score (ACS Risk Calculator).
Time frame: 6 months
Correlation between V-Possum and survival and complication rate.
Survival and rate of complication correlated with the pre-operative frailty score (V-Possum).
Time frame: 6 months
Activity Levels Pre and Post Surgery as measured by the General Practice Physical Activity Questionnaire
General Practice Physical Activity Questionnaire will be used to assess patient reported activity before and after surgery.
Time frame: 6 months
Quality of Life Pre and Post Surgery as measure by the EuroQoL EQ-5D questionnaire
EuroQol EQ-5D Quality of Life questionnaire will be used to assess patient reported quality of life before and after surgery.
Time frame: 6 months
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