Feasability, Validty and Reliability of Inertial Sensors

Hasselt University18 enrolled

Overview

This study has 3 aimes: 1. To investigate the feasibility of using IMUs (Xsens, MVN Studio) during functional tasks to assess upper limb kinematics in pwMS and stroke survivors. On the one hand, the feasibility of performing the tasks will be investigated . On the other hand, does the XSens give valuable data? 2. To investigate the discriminative validity of kinematic measurements of upper limb movements post-stroke and pwMS in comparison with gender and age-matched healthy controls 3. To investigate the test-retest reliability of the kinematic parameters collected during the different functional tasks in pwMS and stroke survivors It is a cross-sectional case-controlled observational study, with 3 different groups: 25 Persons with Multiple sclerosis, 25 stroke patients and 50 healthy controls, matched by age and gender.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Multiple Sclerosis CVA

Interventions

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Inclusion criteria for all participants: Healthy controls, pwsMS and stroke patients * No orthopedic or neuro-muscular impairments in the upper limb * Age \> 18 years * Able to understand and execute the test instructions * Perceived pain in one of the upper limbs of more than 4/10 (Visual Analog Scale) * Able to move a joint (wrist, elbow or shoulder) in the upper limb against gravity without resistance (Medical Research Council) (16). Inclusion criteria for PwMS: \- Diagnosed with MS using McDonald criteria (17) Inclusion criteria Stroke patients * First- ever single, unilateral (ischemic or hemorrhagic) * At least one month after stroke * No apraxia or hemi spatial neglect Exclusion Criteria: Exclusion Criteria for pwMS only: * a relapse 3 months before the start of the study * A change of symptomatic medication during the testing period Exclusion Criteria: \- People with predominantly ataxia or tremor are excluded from the reliability part of this study

Outcomes

Primary Outcomes

kinematic parameter

The data received of the IMU's are the angles of point task achievement (PTA). PTA is defined as the instant when the ROM, needed for successful task execution, was achieved. Different joint angles of PTA will be calculated by MVN BIOMECH software. Matlab (software version R2016b) and excel will be used to process the data.

Time frame: day 2

kinematic parameter

Time frame: day 3

Secondary Outcomes

The Brunnström Fugl Meyer (BFM)

The Brunnström Fugl Meyer (BFM) was used to measure motor control at the body functions and structures level. The upper limb section is applied: shoulder, elbow, forearm, wrist movements and grip

Time frame: day 1

Action Research arm test

which assessed the patient's ability to handle objects varying in size

Time frame: Day 1

Trunk Impairment Scale

To examine the clinimetric characteristics of the Trunk Impairment Scale (TIS). This scale evaluates motor impairment of the trunk after stroke. The TIS scores, on a range from 0 to 23, static and dynamic sitting balance as well as trunk co-ordination. It also aims to score the quality of trunk movement and to be a guide for treatment.

Time frame: day 1

Manual Ability Measure-36 (questionnaire)

Perceived performance on activity level

Time frame: day1