Aortic dissection (AD) is a serious pathology affecting one person for 300 000 habitants per year. In case of complicated AD on the descending aorta, it is necessary to perform an endovascular surgery in association with medical treatment. An endoprosthesis is implanted on the descending thoracic aorta in order to close the main intimal tear. This closure lead to an increase in the thoracic true lumen diameter, a decrease in the thoracic false lumen diameter, a better perfusion of the aortic branches. Furthermore, even in case of open surgical treatment of the ascending aorta it can be necessary to perform an endovascular treatment on the descending aorta, either to prevent and treat aneurysmal evolution or to treat patent malperfusion syndrome. CT and Magnetic Resonance angiography, by the realization of an aortic morphologic evaluation, are the two key imaging exams in the DA. Nevertheless, CT can't provide aortic dynamic evaluation, contrary to MRI. This exam, thanks to the phase-contrast sequence can measure velocity and flow data in vessels, including aorta but also true and false lumen in the AD. Thus, by verifying the perfusion of the aortic true lumen and the aortic branches it is possible to perform an early evaluation of the endovascular treatment of the DA. Actually, only one study has realized an aortic dynamic evaluation on the AD, unfortunately this study was limited to non-operated patients. In order to assess the place of MRI in the AD, the ingestigation propose to determine if phase-contrast MRI is able to evaluate the impact of the endovascular treatment on the hemodynamic state of the aorta and its branches.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
5
Realization of a MRI before and after the endovascular treatment of the aortic dissection. Use of the 4D phase-contrast sequence during the MRI.
Hopital Louis Pradel
Bron, France
Comparative measurement of the flow in the aortic true lumen before and after endovascular treatment of the aortic dissection
The flows are measured in ml/s at several locations of the aortic true lumen. The flows are measured during the two MRI and compared with each other.
Time frame: change from day 0 and day 16
Comparative measurement of the flow in the aortic false lumen before and after endovascular treatment of the aortic dissection
The flows are measured in ml/s at several locations of the aortic false lumen. The flows are measured during the two MRI and compared with each other.
Time frame: change from day 0 and day 16
Comparative measurement of the flow in the aortic branches before and after endovascular treatment of the aortic dissection
The flows are measured in ml/s in the celiac artery, the superior mesenteric artery, the inferior mesenteric artery, the right and left renal artery, the right and left primitive iliac artery. The flows are measured during the two MRI and compared with each other.
Time frame: day 0 and day 16
Comparative measurement of the number of intimal tear identified through 4D phase-contrast MRI relative to the number of intimal tear identified through Angio MRI before endovascular treatment of the aortic dissection
In the 4D phase-contrast MRI, an intimal tear is identified by a streamline going from the true lumen to the false lumen. In the Angio MRI, an intimal tear is identified by the visualization of the passage of the contrast agent from the true lumen to the false lumen.
Time frame: change from day 0 and day 16
Flow measurement through intimal tear with 4 Dimensions (4D) phase-contrast MRI before and after endovascular treatment of the aortic dissection
The intimal tears are identified thanks to the Angio MRI. The flows are measured during the two MRI and compared with each other.
Time frame: change from day 0 and day 16
Comparative measurement through 4D phase-contrast MRI of the shear forces before and after endovascular treatment of the aortic dissection
Shear forces are measured thanks to the 4D phase contrast MRI.
Time frame: change from day 0 and day 16
Comparative measurement through 4D phase-contrast MRI of parietal energy before and after endovascular treatment of the aortic dissection
Parietal energy is measured thanks to the 4D phase contrast MRI.
Time frame: change from day 0 and day 16
Comparative measurement through 4D phase-contrast MRI of the presence of helicoidal flow before and after endovascular treatment of the aortic dissection
The presence of a perpendicular flow to the main aortic flow is identified thanks to the 4D phase contrast MRI. The helicoidal flow is quantified by the degree of rotation between the beginning of the end of the cardiac cycle in millisecond.
Time frame: change from day 0 and day 16
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