Management of Infection Risk in Non-comparative Trial (MINT)

Inclusion Criteria: * Adult patient, aged ≥ 18 years, who signed and dated informed consent form, * Patients affected by VLU or mixed ulcer of predominantly venous origin (ankle brachial pressure index (ABPI) ≥ 0.7 and ≤ 1.3), * Patient willing and able to wear an effective venous compression system every day during the study period, * Patient with at least three of the five inflammatory clinical signs : pain between dressing changes, periwound erythema, local oedema, malodour and presence of heavy exudate. Exclusion Criteria: * Patients under guardianship or protection of vulnerable adult * Pregnancy or breastfeeding women, * Childbearing potential women with no medically-acceptable method of birth control, * Patients included in another clinical study, * Patients with known allergy with hydrocolloid (carboxymethylcellulose CMC), silicone or silver, * Patients with wound covered partially or totally with necrotic tissue, * Patients who had within the 3 months prior the inclusion, deep vein thrombosis * Patients with a serious general disease that deemed to interfere with the treatment period and evaluation * Patients with progressive neoplastic lesions treated by radiotherapy, chemotherapy or hormone therapy * Patients with non-controlled systemic infection by an suitable antibiotic therapy * Patients with clinically infected wound * Patients with wound requiring surgical treatment or for which surgery is scheduled during the study period * Patients with known cancerous lesions