In spite of technological advances, PCI of complex calcified coronary lesions remain a challenge. Observational studies demonstrate that moderate or severe calcifications in lesions to treat are associated with an increase in mortality, in myocardial infarctions, in stent thrombosis, and in complementary revascularizations. Rotational atherectomy is now part of therapeutic armamentarium of interventional cardiologists for the treatment of some complex calcified coronary lesions. Last recommendations of the European Society of Cardiology about revascularizations indicate that rotational atherectomy should be used for "the preparation of calcified or massive fibrotic lesions that cannot be crossed by a balloon or for an optimal dilatation before stenting". However, this technique is not frequently used and limited to high-volume PCI centers. Even though rotational atherectomy demonstrated an improvement in immediate success of complex lesions, the longterm reduction of cardiovascular events after active stenting has not been proved. In observational studies, the results are not consistent because of many selection biases that influence the choice of an angioplasty with rotational atherectomy device (calcifications, severity of the disease). Furthermore, this technique needs operators with a certain amount of experience. The fundamentals of an optimal use of rotational atherectomy remain to be defined (duration and speed of burr, anti-platelet treatments...).
Study Type
OBSERVATIONAL
Enrollment
1,026
angioplasty with rotational atherectomy device on a nonselected population
Hanush Krankenhaus
Vienna, Austria
La clinique des eaux claires
Grenoble, France
Les Nouvelles Cliniques Nantaises
Nantes, France
University Hospital Nimes
Nîmes, France
University Hospital Toulouse
Toulouse, France
Augusta Krankenhaus
Düsseldorf, Germany
St Luke's Hospital
Thessaloniki, Greece
Azienda Sanitaria Universitaria Integrata di Udine
Udine, Italy
University of Verona
Verona, Italy
University Hospital of Bialystok
Bialystok, Poland
...and 6 more locations
Determination of the prognostic impact of a myocardial
Composite safety endpoint collecting cardiovascular events (cardiovascular death, myocardial infarction, target lesion revascularization, stroke, stent thrombosis, coronary bypass)
Time frame: One year
Frequency of angiographic complications for an optimization of PCI by rotational atherectomy
Number of angiographic complications
Time frame: one year
Frequency of in-hospital events
Number of in-hospital events
Time frame: One year
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