The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System

Inclusion Criteria: * Clinical diagnosis, based on investigator assessment, of type 1 diabetes for at least one year, using insulin for at least 1 year and using an insulin pump for at least 6 months. * Familiarity and use of a carbohydrate ratio for meal boluses by participants and families participating. * Age 6-10 years old or 65 years or older * Hemoglobin A1c \<10% * For females of child-bearing potential, not currently known to be pregnant: A negative serum or urine pregnancy test will be required for all females of child-bearing potential. Participants who become pregnant will be discontinued from the study. Also, participants who during the study develop and express the intention to become pregnant within the timespan of the study will be discontinued. * For participants \<18 years old, living with one or more parent/legal guardian knowledgeable about emergency procedures for severe hypoglycemia and able to contact the participant in case of an emergency. * Willing to disable any automated insulin delivery functionality on a personal insulin pump during study, such as Medtronic 670G in auto mode. Predictive low blood glucose suspend, such as Tandem insulin pump with Basal-IQ, will be allowed. * Investigator has confidence that the participant and family can successfully operate all study devices and is capable of adhering to the protocol. * Willingness to switch to lispro (Humalog) or aspart (Novolog) and to use no other insulin besides lispro (Humalog) or aspart (Novolog) during the study. * Total daily insulin dose (TDD) at least 10 U/day. * Willingness not to start any new non-insulin glucose-lowering agent during the course of the trial Exclusion Criteria: * Severe hypoglycemia resulting in seizure or loss of consciousness in the 12 months prior to enrollment. * Diagnosis of Diabetic Ketoacidosis in the 12 months prior to enrollment. * Uncontrolled cardiac disease (e.g. recent myocardial infarction, severe congestive heart failure). * Cerebrovascular accident in the 12 months prior to enrollment. * Uncontrolled resting arterial hypertension (\>160/90 mm Hg). * Conditions that would make use of a CGM difficult (e.g., blindness, severe arthritis, immobility). * Current use of oral/inhaled glucocorticoids or other medications, which in the judgment of the investigator would be a contraindication to participation in the study. * Concurrent use of any non-insulin glucose-lowering agent other than metformin (including GLP-1 agonists, pramlintide, DPP-4 inhibitors, SGLT-2 inhibitors, sulfonylureas). * Hemophilia or any other bleeding disorder * A condition, which in the opinion of the investigator or designee, would put the participant or study at risk * Participation in another pharmaceutical or device trial at the time of enrollment or during the study * Employed by, or having immediate family members employed by Tandem Diabetes Care, Inc., or having a direct supervisor at place of employment who is also directly involved in conducting the clinical trial (as a study investigator, coordinator, etc.); or having a first-degree relative who is directly involved in conducting the clinical trial.