The study will evaluate 2 strategies to remove central venous catheter (CVC): in one part, the insertion of a midline catheter and in the other part, the conventional insertion of peripheral venous catheter (PVC)
Patients will be randomised when the last indication for CVC has disappeared, which means parenteral nutrition or vasopressors administration. They will be randomised either in the midline group or in the PVC group. * In the midline group, a midline catheter will try to be inserted before the 48th hour after last indication for CVC disappeared. * In the PVC group: a PVC will try to be inserted before the 48th hour after last indication for CVC disappeared. If successful, CVC will then be removed. If not, a PVC will try to be inserted daily till success or worthlessness of a venous line or death. The presence of a CVC will be assessed at the 96th hour after disappearance of last CVC indication.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
83
Centre Hospitalier Departemental Vendée
La Roche-sur-Yon, France
% of patient with a successful Removal of CVC at the 96th hour after disappearance of last indication for CVC
A successful removal of CVC is defined as * success of midline/PVC insertion at H96 and consequently CVC removal * and no necessity for insertion of a new CVC within the 96 first hours
Time frame: H96 : 96th hour after disappearance of last indication for CVC
Total number of puncture required for the insertion of a peripheral catheter
Time frame: until 28 days after randomisation
Total number of peripheral catheter used
Time frame: until 28 days after randomisation
Number of new CVC inserted
Time frame: until 28 days after randomisation
Time consumption
Total time of catheterisation, (measured from the entrance in patient room, to the exit)
Time frame: until 28 days after randomisation
Number of blood culture for research of catheter-related bloodstream infection (CRBSI)
Time frame: until 28 days after randomisation
CVC dwell time
Time of central catheter duration (hours)
Time frame: from disappearance of CVC indication to last CVC removal or 28 days after randomisation if still in place
Number of CVC colonized for per 1000 CVC /days
Time frame: until 28 days after randomisation
Number of CVC-associated bacteremia
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Time frame: until 28 days after randomisation
Number of peripheral catheter-associated bacteremia
Time frame: until 28 days after randomisation
ICU length of stay
Time frame: Until discharge from ICU, an expected average of 12 days
Hospital length of stay
Hospital stay in medical and surgical unit (no follow-up and rehabilitation care unit or long stay)
Time frame: Until discharge from hospital, an expected average of 20 days
ICU mortality
Time frame: Until discharge from ICU, an expected average of 12 days
hospital mortality
mortality in medical and surgical unit (no SSR or long stay)
Time frame: Until discharge from hospital, an expected average of 20 days