Subjects with secondary wet age-related macular degeneration(AMD) or recurrent subfoveal choroidal neovascularization (CNV) in only one study eye will be enrolled into the study.
The screening period was 28 days. The classification of CNV will be determined by Fundus Fluorescein Angiography ( FFA ) at the study centers. Subjects will receive intravitreal injections of TAB014 Monoclonal Antibody Injection in one eye ( the study eye ). Subjects will only receive single intravitreal dose.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
TAB014 of 1.25mg(0.05ml)、2.00mg(0.08ml)、2.50mg(0.10ml)
Peking Union Medical College Hospital of Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
RECRUITINGToxicity associated with TAB014 treatment (possibly, probably, or definitively) occurs within 28 days after a single dose of TAB014.
Describe the impairment of vision by examination.
Time frame: Within 12 weeks after administration
Dose-limiting toxicity and adverse reaction
To Assess the dose-limiting toxicity and adverse reaction of TAB014 Monoclonal Antibody Injection.
Time frame: Within 12 weeks after administration
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