The purpose of this study is to assess whether cosmetic investigational product containing NGF-574H is safe and effective in the treatment of androgenic alopecia in asian adults.
NGF-574H is a obtained by collection of paracrine factors secreted by human umbilical cord blood-derived mesenchymal stem cell that was exposed in vitro to an artificially designed environment mimicking alopecia state in hair follicles to prime the composition of the paracrine factors optimized for hair growth. This study is to assess and confirm whether NGF-574H is safe and effective in the treatment of androgenic alopecia in asian adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
84
Hair serum with 5% conditioned media of human umbilical cord blood-derived mesenchymal stem cells
Hair serum without conditioned media of human umbilical cord blood-derived mesenchymal stem cells
Dankook University Hospital
Cheonan, Chung Nam, South Korea
Change in mean total hair density (hair/cm2)
* The hair density by phototrichogram for 24 weeks application, in comparison to initial value (baseline) and/or placebo product. * Measurement of hair density by phototrichogram (Canfield): change in mean total hair density (hair/cm\^2) * Statistical analysis: Time and product effects (p\<0.05)
Time frame: 0, 6, 12 and 24 weeks
Compare visual assessment before and after cosmetic treatment
Visual Assessment using the clinical picture by an investigator: 7 point score (-3 to 3) Visual assessment by a subject (Self-Assessment): 7 point score (-3 to 3)
Time frame: 0, 6, 12 and 24 weeks
Change in mean Telogen hair density
Measurement of telogen hair density, in comparison to initial value (baseline) and/or placebo product.
Time frame: 0, 6, 12 and 24 weeks
Change in mean Anagen hair density
Measurement of anagen hair density, in comparison to initial value (baseline) and/or placebo product.
Time frame: 0, 6, 12 and 24 weeks
Change in hair growth speed
Measurement of hair growth speed, in comparison to initial value (baseline) and/or placebo product.
Time frame: 0, 6, 12 and 24 weeks
Change in hair diameter
Measurement of hair diameter, in comparison to initial value (baseline) and/or placebo product. Measure hair diameter using electronic outside micrometer.
Time frame: 0, 6, 12 and 24 weeks
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