Thoracic Paravertebral Blocks Using a Combination of Ropivacaine and Dexmedetomidine

China Medical University, China

Overview

The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration.

The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration. The effects of dexmedetomidine have only been compared at lower doses. This trial examined the effect of greater dose of dexmedetomidine on thoracic paravertebral block analgesia duration.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Conditions

Thoracic Paravertebral Blocks

Interventions

DexmedetomidineDRUG

combination of ropivacaine and dexmedetomidine 20 ug every time

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients were included in the study if they were ethnic Chinese, * American Society of Anesthesiologists (ASA) physical status I or II, * candidates for general anesthesia undergoing thoracic surgery Exclusion Criteria: * Patients were excluded if they do not want to cooperate with the test, * had a history of radial artery puncture or coronary artery bypass grafting, * had acute vessel trauma,or had been diagnosed with Raynaud' disease, * had suffered from mental or neurological disorders

Locations (1)

the First Hospital of China Medical University

Shenyang, Liaoning, China

Outcomes

Primary Outcomes

Change of analgesia duration

Change of thoracic paravertebral block analgesia duration

Time frame: Change from Baseline to 3 days after surgery

Data from ClinicalTrials.gov

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