In children with cerebral palsy, secondary problems lead to hip dislocation. the purpose of this study is to find out the effects of botulinum toxin A on hip joint dislocation in cerebral palsy patients.
* Design: Prospective study * Inclusion criteria of patient group: who has a cerebral palsy and GMFCS level 3,4,5 * Intervention: applied medication Botulinum A injection (meditox 200unit) * Main outcome measures: The investigators will measure for finding evidence by checking the x-ray photograph, hip adductor and muscles pressure test and electromyography(EMG test) test of hip adductor, abductor and spine muscles.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
In cerebral palsy patients, Botulinum toxin within the allowable dose of 16 U / kg per body weight will injected into both adductor longus, adductor magnus muscle at 3 U / kg, adductor brevis, and gracilis muscle at a dose of 1 U / kg.
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Change from hip adductor and spin muscles electromyography(EMG) test at a month
Use EMG to check the activity of the hip adductor and spine muscles of participants. This figures will give investigators a look at the association with a hip dislocation.
Time frame: once at study, when patient enrolled and every once a month for one year
Whole spine AP and total Hip AP X-ray photograph
Whole spine and total Hip joint are checked with X-ray photograph. and investigators will check the progress of hip dislocation and spinal scoliosis.
Time frame: once at study, when patient enrolled and and after six month for one year
hip adductor muscles pressure meter test
Pressures of hip adductors muscles are measured from pressure meter. and This figures will give investigators a look at the association with a hip dislocation.
Time frame: once at study, when patient enrolled and every once a month for one year
Likert scale
Evaluate the satisfaction of botulinum toxin A injection. Likert scale is a response category that indicates the extent to which the question is for or against. Example) Very satisfied - normal - slightly dissatisfied - very dissatisfied
Time frame: once at study, when patient enrolled and every once a month for one year
Hip and knee joint Range of motion(ROM) test
Measure the range of motion the knee and hip joints.
Time frame: once at study, when patient enrolled and every once a month for one year
CPCHILD sacle
Evaluate the quality of life for patients with cerebral palsy. CPCHILD scale have 6section and each section measures scores by 0 to 5.
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Time frame: once at study, when patient enrolled and every once a month for one year