The Relationship Between CD138 Count of Endometrium and Reproductive Outcome

Reproductive & Genetic Hospital of CITIC-Xiangya148 enrolled

Overview

It's well known, endometritis affects reproductive outcomes. Though CD138 counting as one new diagnosis measure for endometritis, diagnostic criterion of this measure isn't consistent. And if the CD138 counting is correlation to the outcome of reproductive is not clear. Firstly, This study aims to explore the relationship between endometrial CD138 count and pregnancy outcome following frozen embryo transfer in natural cycles. Secondly , the investigators want to find a cut-off value which is related to reproduction outcome.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

148

Conditions

Infertility

Interventions

Endometrial biopsiesPROCEDURE

Endometrial biopsy was performed precisely 7 days after LH surge (LH+7)

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 38 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age between20 and 38 years; * regular menstrual cycles; * body mass index (BMI) ranged from 18 to 25 Exclusion Criteria: * uterine abnormalities; * intrauterine adhesions（moderate - severe）, advanced endometriosis, adenomyosis, untreated hydrosalpinx, uterine fibroids (submucosal fibroids, nonmucosal fibroids \>4.0 cm and/or endometrial pressure)

Locations (1)

Reproductive & Genetic Hospital of CITIC-XIANGYA

Changsha, Hunan, China

Outcomes

Primary Outcomes

CD138 counting

Time frame: 7 days after LH surge (LH+7)

clinical pregnancy rate

Time frame: about 28 days after embryo transfer

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.