Effect of Topical Dexmedetomidine on Intraocular Pressure

Beirut Eye Specialist Hospital49 enrolled

Overview

Evaluate the short-term safety and efficacy of dexmedetomidine (0.0055%) drops on intraocular pressure (IOP) in healthy eyes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Glaucoma Intraocular Pressure

Interventions

DexmedetomidineDRUG

Instillation of eyedrops

Balanced salt solutionDRUG

instillation of eyedrop

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with healthy eyes and no history of glaucoma Exclusion Criteria: * history of glaucoma, IOP \> 24mmHg at baseline, abnormal optic nerve on fundus examination, keratoconus, corneal graft, corneal edema or a history of refractive surgery

Locations (1)

Beirut Eye Specialist Hospital

Beirut, Lebanon

Outcomes

Primary Outcomes

Intraocular pressure change

Taken by aplanation tonometry

Time frame: at presentation, 30 minutes, 4 hours and 24 hours after instillation

Data from ClinicalTrials.gov

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